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Accutane and Alcohol: Is It Safe To Take Them Together?

Medically reviewed by Dr. Po-Chang HsuMay 6, 2024
Written by
On May 6, 2024

Table of Contents

Key Points

  • Accutane is a potent treatment for severe acne, but its use comes with potential side effects and considerations, particularly when combined with alcohol.
  • Side effects of Accutane can include dryness, skin sensitivity, joint pain, liver toxicity, and birth defects if taken during pregnancy.
  • Drinking alcohol while on Accutane can exacerbate its side effects and increase the risk of liver damage due to potential interactions between alcohol and the medication.
  • While moderate alcohol consumption might be considered, it's generally recommended to abstain from alcohol entirely while taking Accutane to ensure treatment effectiveness and safety.
  • To minimize risks if choosing to drink alcohol on Accutane, individuals should limit their intake and do their best to plan.

Accutane is a potent remedy for severe acne, offering hope to many who have battled persistent skin issues. However, the journey to clearer skin isn’t always straightforward, especially when alcohol enters the equation. While it’s widely acknowledged that excessive alcohol consumption can be detrimental to your health, the relationship between alcohol and Accutane is nuanced and often overlooked.

Beyond the perils of alcohol abuse, the interplay between Accutane and alcohol can contain a complex landscape of considerations and potential consequences, including impacts on your liver function, the effects of the medication, and your overall health.

What is Accutane?

Accutane, also known by its generic name isotretinoin, is a prescription medication primarily used to treat severe acne that has not responded adequately to other treatments.[1] It belongs to a class of drugs called retinoids, which are vitamin A derivatives. 

Accutane reduces the production of sebum, an oily substance produced by the skin’s sebaceous glands that can clog pores and contribute to acne formation. By decreasing sebum production, Accutane helps to prevent the formation of new acne lesions and promotes the healing of existing ones. 

Accutane is typically taken orally in the form of capsules and is usually prescribed for several months. It is known for its effectiveness in treating severe acne but is also associated with potential side effects and safety considerations, including risks of birth defects, depression, and liver toxicity.

What Side Effects Can Result From Accutane Use?

Accutane use can lead to a range of potential side effects, some of which can be severe:[2]

  • Dryness: Accutane can cause dryness of the skin, lips, eyes, and mucous membranes. This dryness may lead to irritation, itching, and discomfort.
  • Skin sensitivity: The skin may become more sensitive to sunlight, increasing the risk of sunburn and sun sensitivity reactions.
  • Dry or irritated eyes: Accutane can cause dryness and irritation of the eyes, leading to symptoms such as redness, itching, and blurred vision.
  • Joint and muscle pain: Some individuals may experience joint pain, stiffness, or generalized body aches while taking Accutane.
  • Elevated liver enzymes: Accutane can affect liver function, leading to an increase in liver enzyme levels. Regular monitoring of liver function is typically recommended during treatment.
  • Changes in lipid levels: Accutane may alter lipid levels in the blood, leading to increases in cholesterol and triglyceride levels. Monitoring of lipid levels is important to minimize the risk of cardiovascular complications.
  • Birth defects: Accutane is highly teratogenic, meaning it can cause severe birth defects if taken during pregnancy. Female patients of childbearing age must use effective contraception and adhere to strict pregnancy prevention measures while taking Accutane.
  • Depression and mood changes: Accutane use has been associated with mood changes, depression, and suicidal ideation in some individuals. Patients should be monitored for signs of depression and mental health changes during treatment.
  • Hair thinning or loss: Some individuals may experience temporary hair thinning or loss while taking Accutane. This side effect is usually reversible once treatment is completed.
  • Vision changes: In rare cases, Accutane use may lead to changes in vision, including difficulty seeing at night or decreased night vision.

Can I Drink While Taking Accutane?

It’s generally not recommended to drink while taking Accutane. Combining alcohol with the medication may increase the risk of liver damage and other adverse effects from alcohol/Accutane interactions.[3]

Accutane itself can affect liver function, and alcohol can exacerbate this effect, potentially leading to liver toxicity. Additionally, both Accutane and alcohol can cause dryness and irritation of the skin and mucous membranes, which may be worsened when combined.

To ensure the safety and effectiveness of your treatment, it’s advisable to abstain from alcohol consumption while on Accutane. Always consult with your healthcare provider for personalized guidance regarding medication use and alcohol consumption.

How Can I Lessen the Risks if I Choose to Drink While on Accutane?

If you choose to consume alcohol while on Accutane, it’s crucial to follow specific guidelines to minimize the risks and engage in safe drinking practices:

  • Limit alcohol intake: If you decide to drink alcohol, it's essential to limit your intake to moderate levels. This typically means no more than one standard drink per day for women and two standard drinks per day for men.
  • Avoid binge drinking: Avoid consuming large amounts of alcohol in a short period, as this can increase the risk of adverse effects and may exacerbate Accutane-related side effects.
  • Stay hydrated: Drink plenty of water while consuming alcohol to help mitigate potential dehydration caused by Accutane's side effects, such as dryness.
  • Monitor liver function: As your healthcare provider recommends, regularly monitor your liver function through blood tests. Be vigilant for any signs or symptoms of liver damage, such as abdominal pain, jaundice, or unusual fatigue.
  • Be mindful of side effects: Accutane can cause dryness and irritation of the skin and mucous membranes, which may be exacerbated by alcohol consumption. Be mindful of these side effects and take steps to manage them, such as using moisturizers and lip balms.
  • Avoid other medications that may interact with alcohol: Some medications may interact with alcohol and increase the risk of adverse effects. Consult with your healthcare provider to ensure that any other medications you are taking are compatible with alcohol consumption.
  • Know your limits: Understand how alcohol affects you individually and know your limits. If you experience adverse effects or discomfort while drinking alcohol on Accutane, immediately consult your healthcare provider, and consider abstaining from further alcohol consumption.
  • Plan: If you anticipate drinking alcohol on a particular occasion, consult with your healthcare provider before making any changes to your Accutane dosage schedule. It's essential not to adjust your medication schedule without professional advice, as this can affect treatment efficacy and safety.
  • Communicate with your healthcare provider: Be open and honest with your healthcare provider about your alcohol consumption habits while on Accutane. They can provide personalized guidance and monitor your progress to ensure your safety and well-being.

By following these guidelines and practicing responsible drinking habits, individuals on Accutane can help reduce potential risks associated with alcohol consumption while undergoing acne treatment. However, it’s important to remember that abstaining from alcohol entirely is the safest option while on Accutane. Always prioritize your health and well-being and consult your healthcare provider for concerns or questions.

How Can I Balance My Skincare Needs and Social Life When Using Accutane?

Balancing your skincare needs and social life using Accutane often requires careful planning and prioritization. It’s worth mentioning again that avoiding drinking or doing so in moderation is essential for your overall health. 

From there, it is also important to establish a consistent skincare routine tailored to Accutane’s effects.[4] This routine may include gentle cleansers, moisturizers, and sunscreens to address dryness and sensitivity. Sticking to this regimen diligently can help maintain skin health despite the medication’s side effects. When planning social events or outings, consider their potential impact on your skincare routine. Opt for activities that minimize exposure to harsh environmental factors like excessive sun or harsh weather conditions.

Stay hydrated throughout the day to combat Accutane-induced dryness. Bring a water bottle to social gatherings and prioritize hydration to support your skin’s health. When participating in outdoor activities, wear hats, sunglasses, and sunscreen to shield your skin from UV rays.[5] Be open with friends and family about your skincare needs while on Accutane. Communicate any limitations or precautions you must take and ask for their support in accommodating your needs during social events.

Finding the right balance between skincare and social activities may take time. By implementing these strategies and staying proactive in managing your skincare needs, you can use Accutane to balance your skincare and social life. Remember to prioritize self-care and listen to your body’s needs throughout treatment.

Are You Struggling with Alcohol?

Your well-being matters more than anything else. If you’re struggling with ongoing alcohol use, Soba NJ’s alcohol rehab is here to support you every step of the way. With our compassionate guidance and personalized approach, you can start your journey toward sobriety and rediscover a life filled with clarity, joy, and fulfillment. 

Don’t let alcohol hold you or a loved one back any longer. Take the courageous step forward and connect with Soba NJ today to start your transformational journey towards a healthier, happier you.

Medical Content Writer

Amanda Stevens is a highly respected figure in the field of medical content writing, with a specific focus on eating disorders and addiction treatment. Amanda earned a Bachelor of Science degree in Social Work from Purdue University, graduating Magna Cum Laude, which serves as a strong educational foundation for her contributions.

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Frequently Asked Questions about Accutane and Alcohol

While there isn’t direct evidence that alcohol impacts the effectiveness of Accutane, it’s generally recommended to avoid alcohol consumption during treatment to ensure optimal results. Alcohol can potentially strain the liver, which is also responsible for metabolizing Accutane, possibly affecting its efficacy.

Yes, alcohol consumption can exacerbate some of the side effects associated with Accutane, such as liver toxicity and increased blood lipid levels. Both Accutane and alcohol can individually stress the liver, so combining them may amplify this effect, leading to more severe side effects.

It’s advisable to wait for a bit after stopping Accutane before consuming alcohol. Typically, healthcare providers recommend waiting at least one month after completing the Accutane course to allow your body’s systems to normalize and minimize any potential risks associated with alcohol consumption. However, you must consult your healthcare provider for personalized advice based on your individual health profile.

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